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Jiro Akimoto Selected Research

Talaporfin (talaporfin sodium)

11/2021Preliminary Report: Rapid Intraoperative Detection of Residual Glioma Cell in Resection Cavity Walls Using a Compact Fluorescence Microscope.
12/2020Possible mechanism of heme oxygenase-1 expression in rat malignant meningioma KMY-J cells subjected to talaporfin sodium-mediated photodynamic therapy.
9/2020Synergistic effect of dichloroacetate on talaporfin sodium-based photodynamic therapy on U251 human astrocytoma cells.
9/2020Clinical application of the mirror irradiation technique in photodynamic therapy for malignant glioma.
10/2019First autopsy analysis of the efficacy of intra-operative additional photodynamic therapy for patients with glioblastoma.
3/2019Photodynamic therapy with talaporfin sodium induces dose- and time-dependent apoptotic cell death in malignant meningioma HKBMM cells.
1/2019Intraoperative Photodiagnosis for Malignant Glioma Using Photosensitizer Talaporfin Sodium.
1/2018Photodynamic therapy using talaporfin sodium induces heme oxygenase-1 expression in rat malignant meningioma KMY-J cells.
1/2016Photodynamic Therapy for Malignant Brain Tumors.
8/2015Photodynamic therapy using talaporfin sodium induces concentration-dependent programmed necroptosis in human glioblastoma T98G cells.
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Jiro Akimoto Research Topics

Disease

24Neoplasms (Cancer)
01/2022 - 01/2005
20Glioma (Gliomas)
11/2021 - 07/2008
11Glioblastoma (Glioblastoma Multiforme)
10/2020 - 07/2008
6Brain Neoplasms (Brain Tumor)
03/2020 - 07/2008
5Necrosis
03/2019 - 09/2008
4Astrocytoma (Pilocytic Astrocytoma)
09/2020 - 01/2005
3Meningioma (Meningiomas)
12/2020 - 01/2018
2Disease Progression
06/2018 - 01/2005
2Breast Neoplasms (Breast Cancer)
12/2017 - 01/2005
1Edema (Dropsy)
01/2022
1Germinoma
01/2021
1Germ Cell and Embryonal Neoplasms (Germ Cell Tumor)
01/2021
1Diabetes Insipidus
01/2021
1Hypoxia (Hypoxemia)
12/2020
1Mitochondrial Diseases (Mitochondrial Disease)
09/2020
1Lactic Acidosis
09/2020
1Amyotrophic Lateral Sclerosis (Lou Gehrig's Disease)
02/2020
1Frontotemporal Lobar Degeneration (Degeneration, Frontotemporal Lobar)
02/2020
1Frontotemporal Dementia (Semantic Dementia)
02/2020
1Aneurysm (Aneurysms)
11/2018
1Oculomotor Nerve Diseases (Oculomotor Nerve Palsy)
11/2018
1Hydrocephalus (Hydrocephaly)
06/2018
1Lymphoma (Lymphomas)
04/2018
1Endometrial Neoplasms (Endometrial Cancer)
12/2017
1Phototoxic Dermatitis (Phototoxicity)
01/2017
1Neoplasm Metastasis (Metastasis)
01/2016
1Lung Neoplasms (Lung Cancer)
01/2016
1Erythema
10/2013
1Blister (Bulla)
10/2013
1Exanthema (Rash)
10/2013
1Cysts
04/2013
1Stroke (Strokes)
04/2011

Drug/Important Bio-Agent (IBA)

191-phenyl-3,3-dimethyltriazene (PDT)IBA
12/2020 - 09/2008
18Talaporfin (talaporfin sodium)IBA
11/2021 - 07/2008
13Photosensitizing Agents (Photosensitizers)IBA
11/2021 - 07/2008
5phytochlorinIBA
10/2020 - 07/2008
4Proteins (Proteins, Gene)FDA Link
12/2020 - 01/2018
3Pharmaceutical PreparationsIBA
10/2020 - 12/2014
3Messenger RNA (mRNA)IBA
10/2020 - 07/2008
3Temozolomide (Temodar)FDA LinkGeneric
10/2020 - 10/2014
2Tumor Biomarkers (Tumor Markers)IBA
01/2021 - 05/2010
2Heme Oxygenase-1IBA
12/2020 - 01/2018
2Antineoplastic Agents (Antineoplastics)IBA
10/2020 - 01/2018
2MethyltransferasesIBA
10/2020 - 07/2008
2RNA (Ribonucleic Acid)IBA
10/2020 - 07/2008
2Reactive Oxygen Species (Oxygen Radicals)IBA
09/2020 - 01/2017
2L-Lactate Dehydrogenase (Lactate Dehydrogenase)IBA
03/2019 - 08/2015
2Glial Fibrillary Acidic ProteinIBA
09/2008 - 01/2005
2ChlorophyllIBA
09/2008 - 07/2008
1Capsules (Microcapsules)IBA
01/2022
1Isocitrate Dehydrogenase (Isocitrate Dehydrogenase (NAD+))IBA
01/2021
1Mannose (D-Mannose)IBA
10/2020
1Bevacizumab (Avastin)FDA Link
10/2020
1DNA (Deoxyribonucleic Acid)IBA
10/2020
1UbiquitinIBA
02/2020
1EpitopesIBA
02/2020
1Biomarkers (Surrogate Marker)IBA
03/2019
1Mucin-1 (CA 15-3 Antigen)IBA
01/2019
1Indicators and Reagents (Reagents)IBA
11/2018
1Genetic Markers (Genetic Marker)IBA
04/2018
1Therapeutic UsesIBA
01/2018
1TensinsIBA
12/2017
1Hormones (Hormone)IBA
12/2017
1Phosphoric Monoester Hydrolases (Phosphatases)IBA
12/2017
1Conditioned Culture MediaIBA
08/2015
1A-Form DNA (A-DNA)IBA
12/2014
1O(6)-Methylguanine-DNA MethyltransferaseIBA
10/2014
1NestinIBA
07/2014
1Monoclonal AntibodiesIBA
07/2014
1Keratins (Keratin)IBA
04/2013
1Carcinoembryonic AntigenIBA
04/2013
1Propidium (Propidium Iodide)IBA
01/2013
1PhosphatidylserinesIBA
01/2013
1Caspase 3 (Caspase-3)IBA
01/2013
1S 27IBA
06/2012
1Apoprotein(a) (Apolipoprotein (a))IBA
04/2011
1PlasminogenIBA
04/2011
1Amino AcidsFDA Link
04/2011
1Lipoprotein(a)IBA
04/2011
1LDL Lipoproteins (beta Lipoproteins)IBA
04/2011
1Phosphopyruvate Hydratase (Enolase)IBA
05/2010

Therapy/Procedure

20Photochemotherapy (Photodynamic Therapy)
12/2020 - 09/2008
12Therapeutics
01/2021 - 07/2008
9Semiconductor Lasers
11/2021 - 07/2008
6Lasers (Laser)
09/2020 - 09/2008
4Radiotherapy
01/2021 - 01/2016
3Drug Therapy (Chemotherapy)
01/2021 - 07/2008
2Intravenous Injections
01/2019 - 10/2013
2Chemoradiotherapy
01/2009 - 01/2005
1Precision Medicine
01/2021
1Microvascular Decompression Surgery
11/2018
1Ventriculostomy
06/2018
1Neuroendoscopes
06/2018
1Aftercare (After-Treatment)
01/2018
1Salpingo-oophorectomy
12/2017
1Hysterectomy
12/2017
1Segmental Mastectomy (Lumpectomy)
12/2017
1Cranial Irradiation
01/2016
1Colonic Pouches (S Pouch)
04/2013
1Craniotomy
06/2012